NV → CA · about 223 miles
Las Vegas to Santa Ana bus schedule
Greyhound runs 14 direct buses a week from Las Vegas to Santa Ana. The fastest takes 5 hours 30 minutes; the first bus leaves at 5:50 AM and the last at 2:00 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 5h 30m
- First bus
- 5:50 AM
- Last bus
- 2:00 PM
Timetable
Every bus leaves from Las Vegas Bus Terminal and arrives at Santa Ana East Santa Ana Boulevard 1000. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 5:50 AM | 11:30 AM | 5h 40m | Daily | Greyhound Full timetable |
| 2:00 PM | 7:30 PM | 5h 30m | Daily | Greyhound Full timetable |
Route map
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Where to board in Las Vegas Where you get off in Santa Ana The route of the busiest trip
Where to catch the bus in Las Vegas
Where the bus stops in Santa Ana
- Santa Ana East Santa Ana Boulevard 1000 Map of Santa Ana East Santa Ana Boulevard 1000 (Google Maps)
Return trip: Santa Ana to Las Vegas
Questions
How long is the bus from Las Vegas to Santa Ana?
The fastest direct bus takes 5 hours 30 minutes.
What time is the first bus from Las Vegas to Santa Ana?
The earliest departure is at 5:50 AM (Daily) and the last at 2:00 PM (Daily).
Which bus companies go from Las Vegas to Santa Ana?
Greyhound runs direct buses on this route.
Where do I catch the bus in Las Vegas?
Buses to Santa Ana leave from Las Vegas Bus Terminal.