FL → FL · about 26 miles
Key West to Big Pine Key bus schedule
Greyhound runs 19 direct buses a week from Key West to Big Pine Key. The fastest takes 40 minutes; the first bus leaves at 10:00 AM and the last at 5:00 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 19
- Fastest trip
- 40m
- First bus
- 10:00 AM
- Last bus
- 5:00 PM
Every bus on this route stops at Key West International Airport (EYW).
Timetable
Every bus leaves from Key West Bus Station and arrives at Big Pine Key. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 10:00 AM | 10:40 AM | 40m | Daily | Greyhound Full timetable |
| 1:30 PM | 2:10 PM | 40m | Mon, Tue, Fri, Sat, Sun | Greyhound Full timetable |
| 5:00 PM | 5:40 PM | 40m | Daily | Greyhound Full timetable |
Route map
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Where to board in Key West Where you get off in Big Pine Key The route of the busiest trip
Where to catch the bus in Key West
- Key West Bus Station Map of Key West Bus Station (Google Maps)
Where the bus stops in Big Pine Key
- Big Pine Key Greyhound bus stop Map of Big Pine Key Greyhound bus stop (Google Maps)
Return trip: Big Pine Key to Key West
Questions
How long is the bus from Key West to Big Pine Key?
The fastest direct bus takes 40 minutes; the typical trip is 40 minutes.
What time is the first bus from Key West to Big Pine Key?
The earliest departure is at 10:00 AM (Daily) and the last at 5:00 PM (Daily).
Which bus companies go from Key West to Big Pine Key?
Greyhound runs direct buses on this route.
Where do I catch the bus in Key West?
Buses to Big Pine Key leave from Key West Bus Station.
Does the bus from Key West to Big Pine Key stop at Key West International Airport?
Yes, every one: at Key West Bus Station.