SC → MD · about 442 miles
Greenville to Baltimore train schedule
Amtrak runs 7 direct trains a week from Greenville to Baltimore. The fastest takes 12 hours 30 minutes; every train leaves at 2:23 AM.
Timetable data from · Schedule last changed
- Trains a week
- 7
- Fastest trip
- 12h 30m
- Leaves at
- 2:23 AM
Timetable
Every train leaves from Greenville Amtrak Station and arrives at Baltimore Penn Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 2:23 AM | 2:53 PM | 12h 30m | Thu–Sun | Amtrak Full timetable |
| 2:23 AM | 3:17 PM | 12h 54m | Mon–Fri | Amtrak Full timetable |
Route map
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Where to board in Greenville Where you get off in Baltimore The route of the busiest trip
Where to catch the train in Greenville
- Greenville Amtrak Station Map of Greenville Amtrak Station (Google Maps)
Where the train stops in Baltimore
Return trip: Baltimore to Greenville
Questions
How long is the train from Greenville to Baltimore?
The fastest direct train takes 12 hours 30 minutes; the typical trip is 12 hours 30 minutes.
What time is the first train from Greenville to Baltimore?
Every departure is at 2:23 AM (Daily).
Which rail companies go from Greenville to Baltimore?
Amtrak runs direct trains on this route.
Where do I catch the train in Greenville?
Trains to Baltimore leave from Greenville Amtrak Station.