FL → FL · about 65 miles
Big Pine Key to Key Largo bus schedule
Greyhound runs 19 direct buses a week from Big Pine Key to Key Largo. The fastest takes 2 hours 5 minutes; the first bus leaves at 10:45 AM and the last at 5:45 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 19
- Fastest trip
- 2h 05m
- First bus
- 10:45 AM
- Last bus
- 5:45 PM
Timetable
Every bus leaves from Big Pine Key and arrives at Key Largo Bus Stop. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 10:45 AM | 12:50 PM | 2h 05m | Daily | Greyhound Full timetable |
| 2:15 PM | 4:20 PM | 2h 05m | Mon, Tue, Fri, Sat, Sun | Greyhound Full timetable |
| 5:45 PM | 7:55 PM | 2h 10m | Daily | Greyhound Full timetable |
Route map
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Where to board in Big Pine Key Where you get off in Key Largo The route of the busiest trip
Where to catch the bus in Big Pine Key
- Big Pine Key Greyhound bus stop Map of Big Pine Key Greyhound bus stop (Google Maps)
Where the bus stops in Key Largo
- Key Largo Bus Stop Map of Key Largo Bus Stop (Google Maps)
Return trip: Key Largo to Big Pine Key
Questions
How long is the bus from Big Pine Key to Key Largo?
The fastest direct bus takes 2 hours 5 minutes; the typical trip is 2 hours 5 minutes.
What time is the first bus from Big Pine Key to Key Largo?
The earliest departure is at 10:45 AM (Daily) and the last at 5:45 PM (Daily).
Which bus companies go from Big Pine Key to Key Largo?
Greyhound runs direct buses on this route.
Where do I catch the bus in Big Pine Key?
Buses to Key Largo leave from Big Pine Key Greyhound bus stop.