DE → SC · about 503 miles
Wilmington to Greenville train schedule
Amtrak runs 7 direct trains a week from Wilmington to Greenville. The fastest takes 13 hours 17 minutes; the first train leaves at 4:02 PM and the last at 4:07 PM.
Timetable data from · Schedule last changed
- Trains a week
- 7
- Fastest trip
- 13h 17m
- First train
- 4:02 PM
- Last train
- 4:07 PM
Timetable
Every train leaves from Wilmington and arrives at Greenville Amtrak Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 4:02 PM | 5:24 AM +1 day | 13h 22m | Daily | Amtrak Full timetable |
| 4:07 PM | 5:24 AM +1 day | 13h 17m | Thu from Nov 26 | Amtrak Full timetable |
Route map
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Where to board in Wilmington Where you get off in Greenville The route of the busiest trip
Where to catch the train in Wilmington
Where the train stops in Greenville
- Greenville Amtrak Station Map of Greenville Amtrak Station (Google Maps)
Return trip: Greenville to Wilmington
Questions
How long is the train from Wilmington to Greenville?
The fastest direct train takes 13 hours 17 minutes; the typical trip is 13 hours 22 minutes.
What time is the first train from Wilmington to Greenville?
The earliest departure is at 4:02 PM (Daily) and the last at 4:07 PM (Thu).
Which rail companies go from Wilmington to Greenville?
Amtrak runs direct trains on this route.
Where do I catch the train in Wilmington?
Trains to Greenville leave from Wilmington E Front St.