PA → MD · about 154 miles
Pittsburgh to Frederick bus schedule
Greyhound and OurBus run 21 direct buses a week from Pittsburgh to Frederick. The fastest takes 3 hours 30 minutes; the first bus leaves at 1:30 AM and the last at 6:55 PM.
Timetable data from · Schedule last changed
- Buses a week
- 21
- Fastest trip
- 3h 30m
- First bus
- 1:30 AM
- Last bus
- 6:55 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Bus company |
|---|---|---|---|---|---|
| 1:30 AM | 5:00 AM | 3h 30m | Daily | Pittsburgh PA - Bus Station (PGB) to Frederick MD - Transit Center/MARC Station (FRC) | Greyhound Full timetable |
| 6:30 AM | 10:20 AM | 3h 50m | Daily | Pittsburgh PA - Bus Station (PGB) to Frederick MD - Transit Center/MARC Station (FRC) | Greyhound Full timetable |
| 4:55 PM New | 8:40 PM | 3h 45m | Mon, Fri from Dec 11 | Pittsburgh, PA (University of Pittsburgh- Loading zone on Bigelow Street in front of Cathedral of Learning) to Frederick, MD (Prospect Plaza shopping center, close to Dollar tree at 403 S Jefferson St.) | OurBus Full timetable |
| 5:00 PM | 8:45 PM | 3h 45m | Tue from Nov 24 | Pittsburgh, PA (Carnegie Mellon area- Bus stop at the intersection of Forbes Ave and Morewood, opposite to Carnegie Mellon University Alumni House) to Frederick, MD (Prospect Plaza shopping center, close to Dollar tree at 403 S Jefferson St.) | OurBus Full timetable |
| 5:00 PM | 8:45 PM | 3h 45m | Fri from Nov 20 | Pittsburgh, PA (University of Pittsburgh- Loading zone on Bigelow Street in front of Cathedral of Learning) to Frederick, MD (Prospect Plaza shopping center, close to Dollar tree at 403 S Jefferson St.) | OurBus Full timetable |
| 6:55 PM | 11:35 PM | 4h 40m | Daily | Pittsburgh PA - Bus Station (PGB) to Frederick MD - Transit Center/MARC Station (FRC) | Greyhound Full timetable |
Route map
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Where to board in Pittsburgh Where you get off in Frederick The route of the busiest trip
Where to catch the bus in Pittsburgh
Where the bus stops in Frederick
Return trip: Frederick to Pittsburgh
Questions
How long is the bus from Pittsburgh to Frederick?
The fastest direct bus takes 3 hours 30 minutes; the typical trip is 3 hours 45 minutes.
What time is the first bus from Pittsburgh to Frederick?
The earliest departure is at 1:30 AM (Daily) and the last at 6:55 PM (Daily).
Which bus companies go from Pittsburgh to Frederick?
Greyhound and OurBus run direct buses on this route.
Where do I catch the bus in Pittsburgh?
Buses to Frederick leave from Pittsburgh PA - Bus Station (PGB) and Pittsburgh OurBus bus stop.