FL → FL · about 187 miles
Panama City Beach to Lake City bus schedule
Greyhound runs 7 direct buses a week from Panama City Beach to Lake City. The fastest takes 6 hours 35 minutes; every bus leaves at 12:50 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 6h 35m
- Leaves at
- 12:50 PM
Timetable
Every bus leaves from Panama City Beach Bus Station and arrives at Lake City Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 12:50 PM | 7:25 PM | 6h 35m | Daily | Greyhound Full timetable |
Route map
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Where to board in Panama City Beach Where you get off in Lake City The route of the busiest trip
Where to catch the bus in Panama City Beach
- Panama City Beach Bus Station Map of Panama City Beach Bus Station (Google Maps)
Where the bus stops in Lake City
- Lake City Bus Station Map of Lake City Bus Station (Google Maps)
Return trip: Lake City to Panama City Beach
Questions
How long is the bus from Panama City Beach to Lake City?
The fastest direct bus takes 6 hours 35 minutes.
What time is the first bus from Panama City Beach to Lake City?
Every departure is at 12:50 PM (Daily).
Which bus companies go from Panama City Beach to Lake City?
Greyhound runs direct buses on this route.
Where do I catch the bus in Panama City Beach?
Buses to Lake City leave from Panama City Beach Bus Station.