MS → MS · about 189 miles
Natchez to Clarksdale bus schedule
Delta Bus Lines runs 7 direct buses a week from Natchez to Clarksdale. The fastest takes 4 hours 50 minutes; every bus leaves at 1:55 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 4h 50m
- Leaves at
- 1:55 PM
Timetable
Every bus leaves from Natchez and arrives at Clarksdale. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 1:55 PM | 6:45 PM | 4h 50m | Daily | Delta Bus Lines Full timetable |
Route map
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Where to board in Natchez Where you get off in Clarksdale The route of the busiest trip
Where to catch the bus in Natchez
- Natchez Delta Bus Lines bus stop Map of Natchez Delta Bus Lines bus stop (Google Maps)
Where the bus stops in Clarksdale
- Clarksdale Delta Bus Lines bus stop Map of Clarksdale Delta Bus Lines bus stop (Google Maps)
Return trip: Clarksdale to Natchez
Questions
How long is the bus from Natchez to Clarksdale?
The fastest direct bus takes 4 hours 50 minutes.
What time is the first bus from Natchez to Clarksdale?
Every departure is at 1:55 PM (Daily).
Which bus companies go from Natchez to Clarksdale?
Delta Bus Lines runs direct buses on this route.
Where do I catch the bus in Natchez?
Buses to Clarksdale leave from Natchez Delta Bus Lines bus stop.