TX → MS · about 390 miles
Houston to Biloxi bus schedule
FlixBus and Greyhound run 20 direct buses a week from Houston to Biloxi. The fastest takes 7 hours 40 minutes; the first bus leaves at 12:05 AM and the last at 10:50 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 20
- Fastest trip
- 7h 40m
- First bus
- 12:05 AM
- Last bus
- 10:50 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Bus company |
|---|---|---|---|---|---|
| 12:05 AM | 9:50 AM | 9h 45m | Daily | Houston Bus Station Greyhound to Biloxi MS (BIG) | Greyhound Full timetable |
| 1:05 PM | 10:20 PM | 9h 15m | Daily | Houston Bus Station Greyhound to Biloxi MS (BIG) | Greyhound Full timetable |
| 10:50 PM | 6:30 AM +1 day | 7h 40m | Daily except Tue | Downtown Houston to Biloxi MS (BIG) | FlixBus Full timetable |
Route map
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Where to board in Houston Where you get off in Biloxi The route of the busiest trip
Where to catch the bus in Houston
Where the bus stops in Biloxi
Return trip: Biloxi to Houston
Questions
How long is the bus from Houston to Biloxi?
The fastest direct bus takes 7 hours 40 minutes; the typical trip is 9 hours 15 minutes.
What time is the first bus from Houston to Biloxi?
The earliest departure is at 12:05 AM (Daily) and the last at 10:50 PM (Daily except Tue).
Which bus companies go from Houston to Biloxi?
FlixBus and Greyhound run direct buses on this route.
Where do I catch the bus in Houston?
Buses to Biloxi leave from Downtown Houston and Houston Bus Station Greyhound.