SC → MS · about 518 miles
Greenville to Picayune train schedule
Amtrak runs 7 direct trains a week from Greenville to Picayune. The fastest takes 14 hours 24 minutes; every train leaves at 5:31 AM.
Timetable data from · No schedule changes since at least
- Trains a week
- 7
- Fastest trip
- 14h 24m
- Leaves at
- 5:31 AM
Timetable
Every train leaves from Greenville Amtrak Station and arrives at Picayune Amtrak Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 5:31 AM | 6:55 PM | 14h 24m | Daily | Amtrak Full timetable |
Route map
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Where to board in Greenville Where you get off in Picayune The route of the busiest trip
Where to catch the train in Greenville
- Greenville Amtrak Station Map of Greenville Amtrak Station (Google Maps)
Where the train stops in Picayune
- Picayune Amtrak Station Map of Picayune Amtrak Station (Google Maps)
Return trip: Picayune to Greenville
Questions
How long is the train from Greenville to Picayune?
The fastest direct train takes 14 hours 24 minutes; the typical trip is 14 hours 24 minutes.
What time is the first train from Greenville to Picayune?
Every departure is at 5:31 AM (Daily).
Which rail companies go from Greenville to Picayune?
Amtrak runs direct trains on this route.
Where do I catch the train in Greenville?
Trains to Picayune leave from Greenville Amtrak Station.