FL → FL · about 204 miles
Gainesville to Port St. Lucie bus schedule
FlixBus runs 7 direct buses a week from Gainesville to Port St. Lucie. The fastest takes 5 hours 45 minutes; every bus leaves at 5:20 AM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 5h 45m
- Leaves at
- 5:20 AM
Timetable
Every bus leaves from Gainesville and arrives at Port St Lucie Park & Ride. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 5:20 AM | 11:05 AM | 5h 45m | Daily | FlixBus Full timetable |
Route map
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Where to board in Gainesville Where you get off in Port St. Lucie The route of the busiest trip
Where to catch the bus in Gainesville
Where the bus stops in Port St. Lucie
- Port St Lucie Park & Ride Map of Port St Lucie Park & Ride (Google Maps)
Questions
How long is the bus from Gainesville to Port St. Lucie?
The fastest direct bus takes 5 hours 45 minutes.
What time is the first bus from Gainesville to Port St. Lucie?
Every departure is at 5:20 AM (Daily).
Which bus companies go from Gainesville to Port St. Lucie?
FlixBus runs direct buses on this route.
Where do I catch the bus in Gainesville?
Buses to Port St. Lucie leave from Gainesville FlixBus bus stop.